RNA World — Codon Bias & Amino Acid Symmetry
A simulation framework in R to generate synthetic RNA sequences across five nucleotide profiles and explore codon redundancy, nucleotide biases, melting temperatures and amino acid distributions ( Aberdeen University, Scotland ).
Most highly deviated amino acids from the balanced codon usage profile, illustrating shifts in amino acid frequencies under AT- and GC-biased scenarios.


Taxonomic bias assessment. Major class representation in sampling effort (i.e., observed - ideal). Over- and under-representation of each class are illustrated by the green and orange bars respectively. An inverse hyperbolic-sine transformation was used for the x-axis.
